Oxaliplatin

Early side effects

• Tingling sensations experienced as “pins and needles” in the fingers or feet.
• Sensations of cramps or altered sensitivity around the mouth or throat which may be triggered by cold environment or taking cold food or beverages.
  To prevent or reduce the severity of the condition, avoid the cold and keep yourself warm by covering with a blanket, wearing a sweater and/or taking hot beverages. Your attending nurse may also slow down the infusion.
• Nausea and vomiting may occur for 24 to 48 hours after treatment.
  There are medications available which may prevent or decrease these side effects. If you are given these medications, take them as directed.

Delayed side effects

• A drop in the blood cell counts may occur several days after treatment.
• Abnormal sensation, such as numbness, tingling, or burning sensation may be experienced in the hands or feet. 
• Minimal hair loss may occur.

Inform your doctor if any of the following occurs:

• Fever of 38°C or higher.
• Impairment of sense or experience of abnormal sensation in the limbs which persists several days after administration of the drug.
• Unusual bleeding, bruising or black tarry stools.