Letrozole

• Bone pain, joint pain or muscle ache
• Hot flushes can sometimes occur
  If this occurs, take your tablets at bedtime.
• Tiredness and lack of energy may occur
  If tiredness is a problem, do not drive a car or operate machinery if you are feeling tired. Avoid alcohol as it may make you feel more tired and drowsy.
• Osteoporosis
  Calcium supplementation can reduce or prevent bone thinning.
• Hair thinning may occur
  If this occurs, use a gentle baby shampoo and soft brush.

Inform your doctor if any of the following occurs:

• Severe headache or nausea
• Skin rash
• Chest pain or palpitations
• Dizziness
• Swollen extremities
• Unusual constipation or diarrhea
• For women: Unexpected vagina bleeding or discharge