Lapatinib

Drug Class:	Commonly Known As:	Category:
Dual Kinase Inhibitor	Tykerb®	Cancer-related

Lapatinib - What is it for

Lapatinib is an oral targeted medication used to treat advanced breast cancer. It is normally given together with another oral medication, either Capecitabine or Letrozole.

Lapatinib - Side Effects, Precautions, and Contraindications

What side effects can Lapatinib cause?

Nausea and vomiting
Diarrhea
Palms of the hands or soles of the feet may become numb, sore, red or dry
Especially if Lapatinib is taken together with Capecitabine.
Rash, dry skin, itch
Tiredness and lack of energy

Inform your doctor if any of the following occurs:

Fever of 38°C or higher
Sores or ulcers in mouth and throat
Unusual bleeding, bruising or black tarry stools
Rapid or irregular heartbeat
Chest pain, cough or shortness of breath
Unusual water retention or swelling of the hands or feet
Yellowing of the skin or eyes or dark tea-coloured urine
Side effects become severe

Before taking Lapatinib , what precautions must I follow?

Use effective birth control during treatment with Lapatinib. Inform your doctor if you suspect pregnancy.
Inform your doctor or pharmacist if you are taking any other medication or supplements.

What food or medicine must I avoid when I take Lapatinib ?

Avoid taking grapefruit or its juice while you are on Lapatinib.

Lapatinib - Dosage and How to Use

How should Lapatinib be used?

It is a tablet taken by mouth, usually once daily at around the same time each day. Take the exact number of tablets instructed by your doctor.
Take on an empty stomach i.e. at least 1 hour before or 1 hour after food.

What should I do if I miss a dose?

If you miss a dose of Lapatinib, take the next scheduled dose at your usual dosing time. Do not make up for the missed dose or double dose the next day.