Fertility Drugs (Injection) - Side Effects, Precautions, and Contraindications
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Fertility Injections

Drug Class: Commonly Known As: Category:
Gonal-F, Puregon, Menopur, Rekovelle, Pergoveris, Elonva, Orgalutran, Cetrotide, Decapeptyl, Ovidrelrotide

Fertility Injections - Side Effects, Precautions, and Contraindications

What side effects can Fertility Injections cause?

Common side effects include:
  • Nausea, vomiting
  • Stomach pain or swelling, bloating
  • Pelvic pain and discomfort
  • Breast tenderness
  • Headache
    • You may take Paracetamol to manage headaches.
  • Injection site reactions (such as bruising, pain, redness, swelling and itching)
    • You should change injection sites daily to reduce possible injection site reactions.

Inform your doctor if these side effects become severe and bothersome.

Ovarian Hyperstimulation Syndrome (OHSS) happens when too many ovarian follicles have developed in response to the usual dosage of medication. OHSS is usually mild and only causes a slight lower abdominal discomfort in most cases. Although it is not common, it may still need medical attention as it can be potentially life threatening, if left untreated in severe cases. 

You may be developing OHSS if you experience some or all of the following symptoms:

  • Pain and lower abdominal discomfort that do not go away
  • Feeling sick and vomiting
  • Bloatedness and pain in the stomach area
  • Shortness of breath
  • Dehydration
  • Reduction of urine volume
  • Abdominal pain

If any of the symptoms above worsen of do not go away, you should see your healthcare professional immediately.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Fertility Injections , what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are pregnant or breastfeeding.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.
  • You have a known or suspected cancer or tumour of the ovary, breast, uterus.
  • You have ever had twisting of an ovary (ovarian torsion).

What food or medicine must I avoid when I take Fertility Injections ?

  • Updated on 10/31/2022 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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