Dacarbazine

Early side effects

• Nausea, vomiting and loss of appetite may occur.
  There are medications available, which may prevent or decrease these side effects. If you are given these medications, take them as directed.
• Diarrhea may occur.
• Pain at the site of injection may occur.
• Facial flushing or tingling may occur during treatment. This should only last for a few minutes.
• Red, itchy skin rash may appear.
• Flu-like symptoms may occur such as mild fever, muscle ache and tiredness.

Delayed side effects

• A drop in the white blood cell counts may occur 10 to 14 days after treatment.
• Temporary hair loss or thinning may begin 2 to 3 weeks after treatment.

Inform your doctor if any of the following occurs:

• Fever of 38°C or higher.
• Sore throat, hoarseness or mouth sores.
• Redness, pain or swelling at injection site.
• Unusual bleeding, bruising or black tarry stools.

• Avoid prolonged exposure to sunlight as Dacarbazine may cause increased sensitivity to sunlight. The use of a sunscreen and/or protective clothing may be helpful.