Medium-Chain Acyl-CoA Dehydrogenase Deficiency

How is MCADD managed?

The management of MCADD includes:

• Avoidance of fasting
• Use of emergency treatment protocol
• Use of emergency regimen (provided by dietitian)
• Carnitine supplementation in some cases (if carnitine level is low)
• Intravenous glucose drip in the hospital if the child vomits or refuses to eat
• Avoidance of concentrated sources of mediumchain triglycerides (MCT), like MCT oil and specialised products with high MCT oil content

Is there any monitoring required?

As MCADD is a lifelong condition, there will be regular monitoring of growth and development, and assessment of diet and nutrition.

Most people with MCADD, with appropriate care and management, go on to live long, healthy lives.

What is an emergency letter and when do I need it?

An emergency letter is a letter provided by the metabolic clinic. If you have not received a letter, please contact your metabolic clinic and ask for one.

Bring the letter to the emergency department in the event of an illness or poor eating.