Condition & Treatment

Marfan Syndrome - Other Information

How likely will I have a child with Marfan syndrome if I have it?

If a parent has Marfan syndrome, the risk of having a child inherit the gene that causes it is 50% in every pregnancy.

How likely will I have another child with Marfan syndrome if neither my spouse nor I have it?

In about 25% of cases, Marfan syndrome is the result of a spontaneous change (mutation) in the genetic material of the sperm or egg at conception in families with no previous history of the disease.

In such cases, the risk of having another child with the disorder is low (< 1%).

Marfan syndrome is a lifelong condition. Should you require financial assistance or emotional support, please approach your doctor for referral to a medical social worker.

Support Groups
Club Rainbow Singapore Club Rainbow Singapore supports and empowers children with chronic illnesses and their families by providing relevant compassionate services in their journey. Tel: 6377 1789 Email: [email protected] www.clubrainbow.org The Marfan Foundation www.marfan.org

Download the Marfan Syndrome brochure.

References

Marfan Syndrome: Public education. (2024). Marfan Syndrome, 1–8. https://doi.org/10.36255/marfan-syndrome-public-education
Marfan syndrome symptoms, causes, treatment: Nord. National Organization for Rare Disorders. (2024, March 20). https://rarediseases.org/rare-diseases/marfan-syndrome/
Marfan syndrome. Marfan Foundation. (2022, October 6). https://marfan.org/conditions/marfan-syndrome/
Centers for Disease Control and Prevention. (n.d.). About Marfan syndrome. Centers for Disease Control and Prevention. https://www.cdc.gov/heart-disease/about/marfan-syndrome.html