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Prof Lam Su Ping Carolyn

MBBS, PhD, MRCP, MS, FACC, FAMS, FESC

Senior Consultant

National Heart Centre Singapore

Specialty: Cardiology

Clinical Interest: Heart Failure

Conditions Treated by this Doctor:
Cardiovascular Disease, Heart Failure, Women’s Heart Disease.

Clinical Appointments

Senior Consultant Department of Cardiology National Heart Centre Singapore
Director of Women’s Heart Health National Heart Centre Singapore

Academic Appointments

Research EXCO SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme

Profile

Professor Carolyn Lam is a Senior Consultant from the Department of Cardiology and Director of Women's Heart Health at the National Heart Centre Singapore, having pioneered the first Women’s Heart Clinic in Singapore. Academically, she serves as a tenured Full Professor at the Duke-National University of Singapore, having also graduated from the Standford Executive Programme in 2015, and obtained a PhD at the University Medical Centre Groningen, the Netherlands in 2016. In the field of MedTech, Prof Lam is co-founder of Us2.ai, an award-wining startup dedicated to the automation of the fight against heart disease by applying artificial intelligence to echocardiography (ultrasound of the heart).

Prof Lam is a world-renowned specialist in heart failure (particularly heart failure with preserved ejection fraction [HFpEF]). Her work in the PARAGON-HF and EMPEROR-Preserved trials led to the first FDA-approved treatment for HFpEF and the first robustly positive clinical outcomes trial in HFpEF to-date, respectively. She leads several multinational global and regional clinical trials, and has received numerous prestigious awards and global recognition for her work. Her recent appointments on the 2021 European Society of Cardiology Heart Failure Guidelines Task Force, and as International Honorary Fellow of the Heart Failure Society of America 2021, attest to her contributions in both cardiology and research fields.

Prof Lam is a proud recipient of the National Medical Research Council (NMRC) Senior Investigator Clinician Scientist Award in 2020, and served as the Founding Programme Lead of A*STaR’s Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT) and Principal Investigator of ASIAN-HF (a multinational study across 11 Asian countries). In 2019, She initiated the Asian Diabetes Outcomes Prevention Trial (ADOPT), an ongoing trial involving 5 countries and aimed at reducing the cardiovascular adverse outcomes of diabetes in Asian patients.

She has published with over 350 articles in major high impact journals including New England Journal of Medicine, Journal of the American Medical Association (JAMA), Lancet, Circulation, and European Heart Journal; and has been recognised as a World Expert by Expertscape’s PubMed-based algorithms (top 0.1% of scholars writing about Heart Failure over the past 10 years; Heart Failure: Worldwide - Expertscape.com). Besides being an Associate Editor for Circulation (top Cardiology Journal) and European Journal of Heart Failure, she is also the lead author of the chapter on HFpEF for Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 12th Edition - the award-winning textbook trusted by generations of cardiologists for the latest, most reliable guidance in the field.

Prof Lam serves as a consultant on several global advisory boards for cardiovascular disease, as a member of the Executive Committees of global heart failure trials, and as an Associate Editor for Circulation and the European Journal of Heart Failure. Finally, she is heard weekly on the global podcast "Circulation On The Run" and seen regularly on television as the Resident Doctor of the health programme "Body and Soul" by MediaCorp Singapore.

Education

Royal College of Physicians of Edinburgh Fellow of the Royal College of Physicians (FRCP), 2018
University of Groningen, NLD PhD, 2016
Stanford Graduate School of Business, Stanford Executive Programme, 2015
Framingham Heart Study, MA, US, Fellowship (Clinical & Genetic Epidemiology), 2010
Mayo Clinic, Rochester MN, US, Master of Biomedical Science, 2009
Mayo Clinic, Rochester MN, US, Fellowship (Heart Failure & Advanced Cardiology), 2009
Ministry of Health, Singapore Specialist Accreditation (Cardiology), 2005
National University of Singapore, Bachelor of Medicine and Bachelor of Surgery (MBBS), 1998

Professional Appointments and Committee Memberships

Professional Appointments

2022-23 Content Expert, Clinical Teacher and Clinical Practice Facilitator, Lee Kong Chian School of Medicine
2021-present Scientific Lead of Imaging – Echo and Theme Principal Investigator HFpEF and Women’s Health and Heart Muscle Disease, National Heart Research Institute Singapore (NHRIS)
2020-present Principal Lead of Clinical Trials & Trials Network, National Heart Research Institute Singapore (NHRIS)
2020 Degree of Doctor Philosophiae causa, University of Oslo
2019 SingHealth Investigational Medicine Unit Executive Committee, EXCO member
2019 Adjunct Teaching Faculty Member, Lee Kong Chian School of Medicine
2019 Conjoint Professor, University of New South Wales

Committee Memberships

2021-2026 Member, National Clinical Trials Strategy Committee, Ministry of Health & National Medical Research Council
2021-Present Scientific Expert, Global Data Collaborative for Cardiovascular Population Health, Microsoft and Novartis Foundation
2021 European Society of Cardiology Heart Failure Guidelines Task Force
2021 Co-Chair, Roadmap for Digital Health in Cardiology, World Heart Federation (WHF)
2020-Present Member, ESC Global Affairs Committee
2018, 2020-2023 Full Member, Committee of the Education & Management Division on Clinical Applications of Cardiac Bio-Markers (C-CB) for International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)
2019 Member, Global Health Programme Committee Group, European Society of Cardiology
2019 Asia Pacific Representative, World Heart Federation Science Committee
2019 Worldwide CardioDiabetes Board (Member), Worldwide Diabetes Foundation
2019 NHLBI Atrial Fibrillation Working Group, NIH/NHLBI
2016-2018 Local Review Panel Member, Clinician Scientist-Individual Research Grant, National Medical Research Council
2018-2020 Member, Global Affairs Committee, European Society of Cardiology
2018-2020 HFpEF Committee Member, Heart Failure Association, European Society of Cardiology
2018 Member, Global Health Programme Committee Group, European Society of Cardiology
2018 Co-Chair, International HF Working Group, American College of Cardiology (ACC)
2017 Scientifc Advisor, Clinical Trials Coordinating Centre, SingHealth
2017 Affiliate Member, SingHealth Duke-NUS Institute of Precision Medicine (PRISM)
2017 Member, Lancet Commission on Cardiovascular Disease in Women
2014, 2017 Clinician Scientist-Individual Research Grant (CS-IRG) Local Review Panel Member, National Medical Research Council Member
2017 Member, International Federation of Clinical Chemistry & Laboratoy Medicine (IFCC) Task Force
2016 HFpEF Committee Member, Heart Failure Association, European Society of Cardiology
2016 Committee Member – Strategic Thrust #3 "Strenthen Collaborations", SingHealth Duke-NUS Research
2015 Fellow, Academy of Medicine Singapore
2015 Working Group for Heart Failure Outcomes, International Consortium for Health Outcomes Measurement
2015 Writing Group, Consensus Document for the Diagnosis of HFpEF, Heart Failure Association, European Soceity of Cardiology
2015 Workgroup, Clinical Practice Guidelines on Heart Failure, Ministry of Health
2015 National Lead, European Atherosclerosis Society Familial Hypercholesterolemia Studies Collaboration
2015 Member, Research Training Review Panel, Ministry of Health SAB Research Committee
2014 Fellow, ASEAN Federation of Cardiology
2014 Chairperson, Asia Pacific Association of Women's Cardiovascular Disease
2013 Board Member, Singapore Heart Foundation
2012 Member, Singapore Cardiac Society
2012 Fellow, European Society of Cardiology
2012 Fellow, American College of Cardiology
2010 Faculty Member, Faculty of 1000 Medicine
2001 Member, Royal College of Physicians

Awards

2022 Experscape Expert in Obesity
2021 Clarivate’s Highly Cited Researcher 2021 in the category of Clinical Medicine
- https://recognition.webofscience.com/awards/highly-cited/2021/
2021 Recognized as a World Expert by Expertscape’s PubMed-based algorithms
- Top 0.1% of scholars writing about Heart Failure over the past 10 years
- Heart Failure: Worldwide - Expertscape.com
2021 International Honorary Fellow of the Heart Failure Society of America 2021
2020 Lee Foundation 2020 (ADOPT research) – Received S$2.28M - 'Arresting Heart Disease in Diabetics' under the Singhealth Duke NUS Cardiovascular Sciences Academic Clinical Programme
2020 2nd prize for SingHealth Duke-NUS Research Team Award 2020 - "Asian neTwork for Translation Research and Cardiovascular Trials (ATTRaCT)"
2019 Paul Dudley White International Scholar Award – To Recognize the Authors with the Highest Ranked Abstract from New Zealand at Scientific Sessions 2019
2019 National Medical Research Council Clinician Scientist Award (Senior Investigator Category)
2019 A*STAR Awards 2019: Borderless Award (awarded to ATTRaCT program; PI/ program director: Carolyn Lam SP)
2019 GCEO – Outstanding Clinical Researcher Award
2019 Bronte-Stewart Memorial Lectureship at the University of Glasgow
2018 Singapore Health Quality Award 2018 – Outstanding & Commendable service for the period of April 2016 to March 2017, 2018
2017 ESC Grants to attend Women Transforming Leadership Programme at Oxford University
2017 LEAP Award – EXCELLENCE (For 'Honours' Grade) for ACP Mentor
2015 Rosalind Franklin Fellowship Award
2014 Junior Chamber International (JCI) Ten Outstanding Young Persons of the World for 2014 Singapore Honouree Winner for Medical Innovation
2013 National Medical Research Council Clinician Scientist Award (Senior Investigator category)
2013 Singapore Women's Weekly Great Women Of Our Times (Winner)
2012 L'Oreal Women In Science
2012 InterAcademy Medical Panel Young Physician Leader (World Health Summit, Berlin)
2012 Investigational Medicine Unit Bridging Fund Award
2010 National Medical Research Council Clinician Scientist Award (Investigator category)
2010 European Society of Cardiology Moderated Poster Award Winner
2009 Evans Department of Medicine Research Days, Boston University School of Medicine, (3rd Prize for Clinical/Patient Based Research)
2008 American Heart Association Women in Cardiology Trainee Award for Excellence
2006 Jay N Cohn New Investigator Clinical/ Integrative Physiology Award Competition (First prize)
2005 Liew Weng Chee Scholarship
2004 China Medical Board Scholarship
2004 Singapore Cardiac Society Young Investigator Award (First prize)
2003 Society of Internal Medicine, San Diego (Finalist), 4th Annual International Poster Competition, American College of Physicians/ American
2000 Society of Infectious Disease (Singapore) Award for the 7th Western Pacific Congress of Chemotherapy and Infectious Diseases
1997-1998 Yeoh Khuan Joo Gold Medal (Surgery)
1997-1998 Singapore Medical Association Bronze Medal
1997-1998 Faculty of Medicine Dean's List Award
1996-1997 Faculty of Medicine Dean's List Award
1995-1996 Medical Alumni Association Bronze Medal
1994-1996 Faculty of Medicine Dean's List Award

Research Interests

Heart Failure
Clinical Trials
Echocardiography
Hemodynamics
Biomarkers
Sex Differences
Epidemiology

Publications

Jasper Tromp, Wouter Ouwerkerk, Tiew-Hwa K. Teng, John G. F. Cleland, Sahiddah Bamadha, Christiane E. Angermann, Ulf Dahlstrom, Wan Ting Tay, Kenneth Dickstein, Georg Ertl, Mahmoud Hassanein, Sergio V. Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Sean P Collins, Gerasimos Filippatos, Carolyn SP Lam. Global Disparities in Prescription of Guideline-Recommended Drugs for Heart Failure with Reduced Ejection. European Heart Journal. Feb 2022. JIF: 22.673
Carolyn SP Lam. How to incorporate sex and gender into the design of cardiovascular clinical trials. Circulation. 2022 Feb 15;145(7):499-501. doi: 10.1161/CIRCULATIONAHA.121.058771. JIF: 23.603
Subodh Verma, Nitish K Dhingra, Javed Butler, Stefan D Anker, Joao Pedro Ferreira, Gerasimos Filippatos, James L Januzzi, Carolyn SP Lam, Naveed Sattar, Barbara Peil, Matias Nordaby, Martina Brueckmann, Stuart JPocock, Faiez Zannad Milton Packer. Empagliflozin in the treatment of heart failure with reduced ejection fraction in addition to background therapies and therapeutic combinations (EMPEROR-Reduced): a post-hoc analysis of a randomised, double-blind trial. Lancet Diabetes & Endocrinology. 2021 Nov 30;S2213-8587(21)00292-8. doi: 10.1016/S2213-8587(21)00292-8. Online ahead of print. JIF: 25.340
Birgit Vogel, Monica Acevedo, Yolande Appelman, C Noel Bairey Merz, Alaide Chieffo, Gemma A Figtree, Mayra Guerrero, Vijay Kunadian, Carolyn SP Lam, Angela H E M Maas, Anastasia S Mihailidou, Agnieszka Olszanecka, Jeanne E Poole, Clara Saldarriaga, Jacqueline Saw, Liesl Zühlke, Roxana Mehran. The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030. The Lancet. 2021 Jun 19;397(10292):2385-2438. doi: 10.1016/S0140-6736(21)00684-X. Epub 2021 May 16. JIF: 60.392
Carolyn SP Lam, Chinthanie Ramasundarahettige, Kelley R.H. Bran ch,Naveed Sattar, Julio Rosenstock, Richard Pratley, Stefano Del Prato, Renato D. Lopes, Elisabeth Niemoeller, Nardev S. Khurmi, Seungjae Baek, Hertzel C. Gerstein. Efpeglenatide and Clinical Outcomes with and without Concomitant Sodium-Glucose Co-Transporter-2 Inhibition Use in Type 2 Diabetes: Exploratory Analysis of the AMPLITUDE-O Trial. Circulation. November 2021. JIF: 23.603
Carolyn SP Lam, João Pedro Ferreira, Egon Pfarr4, David Sim, Hiroyuki Tsutsui, Stefan D. Anker, Javed Butler, Gerasimos Filippatos, Stuart J. Pocock, Naveed Sattar, Subodh Verma, Martina Brueckmann, Janet Schnee, Daniel Cotton, Faiez Zannad, Milton Packer. Regional and Ethnic Influences on the Response to Empagliflozin in Patients With Heart Failure and a Reduced Ejection Fraction: the EMPEROR-Reduced trial. European Heart Journal. May 2021. JIF: 22.673
Carolyn SP Lam, Greg D Gamble, Lieng H Ling, David Sim, Kui Toh Gerard Leong, Poh Shuan Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Tze P Ng, Vicky A Cameron, Katrina Poppe, Mayanna Lund, Gerry Devlin, Richard Troughton, A. Mark Richards*, Robert N Doughty *(*Co-senior authors); Mortality Associated With Heart Failure With Preserved Versus Reduced Ejection Fracton In A Prospective International Multi-Ethnic Cohort Study. European Heart Journal. 2018 May 21;39(20):1770-1780. doi: 10.1093/eurheartj/ehy005. JIF: 22.673
Subodh Verma, Nitish K. Dhingra, Javed Butler, Stefan D. Anker, Joao Pedro Ferreira, Gerasimos Filippatos, James L. Januzzi, Carolyn SP Lam, Naveed Sattar, Barbara Peil, Matias Nordaby, Martina Brueckmann, Stuart J. Pocock, Faiez Zannad, and Milton Packer for the EMPEROR-Reduced Trial Committees and Investigators. Efficacy and Safety of Empagliflozin According to Doses and Combinations of Other Treatments for Heart Failure: A Post Hoc Analysis of the EMPEROR-Reduced Randomized Trial. The Lancet Diabetes & Endocrinology. November 2021. JIF: 25.340
Jasper Tromp, Milton Packer, Carolyn SP Lam. The diverging role of epicardial adipose tissue in heart failure with reduced and preserved ejection fraction: not all fat is created equal. European Journal of Heart Failure. 2021 Oct 16. doi: 10.1002/ejhf.2363. JIF: 11.627
Carolyn SP Lam, Hillary Mulder, Yuri Lopatin, Jose B Vazquez-Tanus, David Siu, Justin Ezekowitz, Burkert Pieske, Christopher M O'Connor, Lothar Roessig, Mahesh J Patel, Kevin J Anstrom, Adrian F Hernandez, Paul W Armstrong, VICTORIA Study Group. Blood Pressure and Safety Events With Vericiguat in the VICTORIA Trial. Journal of the American Heart Association. 2021 Nov 6;e021094. doi: 10.1161/JAHA.121.021094. Epub 2021 Nov 6. JIF: 4.605
Jasper Tromp, Wouter Ouwerkerk, Dirk J. van Veldhuisen, Hans L. Hillege, A. Mark Richards, Peter van der Meer, Inder S. Anand, Carolyn SP Lam (co-corresponding author), Adriaan A. Voors. A Systematic Review and Network-Meta-Analysis of Pharmacological Treatment of Heart Failure with Reduced Ejection Fraction. JACC Heart Failure September 2021. JIF: 8.750
S.D. Anker, J. Butler, G. Filippatos, J.P. Ferreira, E. Bocchi, M. Böhm, H.-P. Brunner–La Rocca, D.-J. Choi, V. Chopra, E. Chuquiure-Valenzuela, N. Giannetti, J.E. Gomez-Mesa, S. Janssens, J.L. Januzzi, J.R. Gonzalez-Juanatey, B. Merkely, S.J. Nicholls, S.V. Perrone, I.L. Piña, P. Ponikowski, M. Senni, D. Sim, J. Spinar, I. Squire, S. Taddei, H. Tsutsui, S. Verma, D. Vinereanu, J. Zhang, P. Carson, Carolyn SP Lam, N. Marx, C. Zeller, N. Sattar, W. Jamal, S. Schnaidt, J.M. Schnee, M. Brueckmann, S.J. Pocock, F. Zannad, and M. Packer, for the EMPEROR-Preserved Trial Investigators. Empagliflozin in Heart Failure with a Preserved Ejection Fraction. The New England Journal of Medicine. August 2021. JIF: 74.699
Wan Ting Tay, Tiew-Hwa Katherine Teng, Oliver Simon, Wouter Ouwerkerk, Jasper Tromp, Robert N Doughty, Mark Richards, Chung-Lieh Hung, Yan Qin, Than Aung, Inder Anand, Carolyn SP Lam. Readmissions, death and its associated predictors in heart failure with preserved versus reduced ejection fraction. Journal of the American Heart Association. 2021 Nov 16;10(22):e021414. doi: 10.1161/JAHA.121.021414. Epub 2021 Oct 20. JIF: 4.605
Hertzel C. Gerstein, Naveed Sattar, Julio Rosenstock, Chinthanie Ramasundarahettige, Richard Pratley, Renato D. Lopes, Carolyn SP Lam, Nardev S. Khurmi, Laura Heenan, Stefano Del Prato, Leanne Dyal, Kelley Branch. Efpeglenatide, Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes. June 2021. New England Journal of Medicine. doi:10.1056/NEJMoa2108269 JIF: 74.699
Shih-Chieh Chien, Chanchal Chandramouli, Chi-In Lo, Chao-Feng Lin, Kuo-Tzu Sung, Wen-Hung Huang, Yau-Huei Lai, Chun-Ho Yun, Cheng-Huang Su, Hung-I Yeh, Ta-Chuan Hung, Chung-Lieh Hung, Carolyn SP Lam. Associations of obesity and malnutrition with cardiac remodelling and cardiovascular outcomes in Asian adults: A cohort study (Short title: Double burden of obesity and malnutrition on cardiac outcomes in Asians). PLOS Medicine. May 2021. JIF: 10.500
Carolyn SP Lam, Scott D. Solomon. Nomenclature in Heart Failure: Heart Failure with Reduced, Mildly Reduced and Normal Ejection Fraction. Journal of the American College of Cardiology. April 2021. JIF: 18.639
Martin Cowie and Carolyn SP Lam. Remote monitoring and digital health tools in cardiovascular disease management. Nature Reviews Cardiology. 6 April 2021. https://doi.org/10.1038/s41569-021-00548-x. JIF: 20.260
Jasper Tromp, Jennifer A. Bryant, Xuanyi Jin, Gijs van Woerden, Salma Asali, Han Yiying, Oi Wah Liew, Jenny Chong Pek Ching, Fazlur Jaufeerally, Seet Yoong Loh, David Sim, Sheldon Lee, Dinna Soon, Wan Ting Tay, Milton Packer, Dirk J. van Veldhuisen, Calvin Chin, A Mark Richards, Carolyn SP Lam. Epicardial fat in heart failure with reduced versus preserved ejection fraction. European Journal of Heart Failure. 16 March 2021. doi:10.1002/ejhf.2156. JIF: 11.627
Carolyn SP Lam, Robert Wood, Muthiah Vaduganathan, Hector Bueno, Alex Chin, Gabriela Luporini Saraiva, Elisabeth Sörstadius, Theo Tritton, Joseph Thomas, Lei Qin. Contemporary economic burden in a real-world heart failure population with Commercial and Medicare Supplemental Plans. Clinical Cardiology. 11 March 2021. https://doi.org/10.1002/clc.23585 JIF: 2.248
Carolyn SP Lam, Avraham Karasik, Cheli Melzer-Cohen,,Matthew A. Cavender, Shun Kohsaka, Anna Norhammar, Marcus Thuresson, Hungta Chen, Eric Wittbrodt, Peter Fenici, Mikhail Kosiborod on behalf of the CVD-REAL Investigators and Study Group. Association of SGLT2 inhibitors with outcomes in Type 2 diabetes with reduced and preserved left ventricular ejection fraction — Analysis from the CVD-REAL 2 Study. Diabetes, Obesity and Metabolism. February 2021. https://doi.org/10.1111/dom.14356 JIF: 5.9
Jasper Tromp, Brian L. Claggett, Jiankang Liu, Alice M. Jackson, Pardeep S. Jhund, Lars Kober, Jiri Widimsky, Sergey Boytsov, Vijay Chopra, Inder S. Anand, Junbo Ge, Chen-Huan Chen, Aldo P. Maggioni, Felipe Martinez, Milton Packer, Marc A. Pfeffer, Burkert Pieske, Margaret M. Redfield, Jean L. Rouleau, Dirk J. Van Veldhuisen, Faiez Zannad, Michael R. Zile, Adel R. Rizkala, Akiko Inubushi-Molessa, Martin P. Lefkowitz, Victor C. Shi, John J.V. McMurray, Scott D. Solomon, Carolyn SP Lam on behalf of the PARAGON-HF Investigator. Global Differences in Heart Failure in Preserved Ejection Fraction: the PARAGON-HF trial. Circulation: Heart Failure. February 2021. JIF: 5.420
Jasper Tromp*, Samantha M.A. Paniagua*, Emily S. Lau, Norrina B. Allen, Michael J. Blaha, Ron Gansevoort, Hans Hillege, Douglas E. Lee, Daniel Levy, Vasan S. Ramachandran, Pim van der Harst, Wiek van Gilst, Martin G. Larson, Sanjiv J. Shah*, Rudolf A. de Boer*, Carolyn SP Lam*#, Jennifer E. Ho*#. Age-dependent Associations of Risk Factors with Heart Failure. British Medical Journal February 2021. JIF: 30.223 *these authors contributed equally #co-last author
THK Teng, WT Tay, AM Richards, TSM Chew, I Anand, W Ouwerkerk, C Chandramouli, W Huang, C Lawson, UT Kadam, J Yap, SL Lim, C-L Hung, MR MacDonald, SY Loh, W Shimizu, J Tromp, Carolyn SP Lam. Socioeconomic status and outcomes in heart failure with reduced ejection fraction from Asia. Circulation: Cardiovascular Quality and Outcomes. 24 March 2021. doi: 10.1161/CIRCOUTCOMES.120.006962. JIF: 5.07
Chorh Chuan Tan, Carolyn SP Lam, David B. Matchar, Yoong Kang Zee, John E.L. Wong. Singapore’s Healthcare System: Key features, Challenges and Shifts. The Lancet. 2021 Sep 18;398(10305):1091-1104. doi: 10.1016/S0140-6736(21)00252-X. Epub 2021 Sep 2. JIF: 60.392
Kanako Teramoto, Jasper Tromp, Carolyn SP Lam. Heart Failure or Heart Success? Cardiovascular Research Onlife. https://doi.org/10.1093/cvr/cvab022 13 February 2021. JIF: 8.68
Janice Y Chyou, Wan Ting Tay, Inder S Anand, Tiew-Hwa Katherine Teng, Jonathan JL Yap, Michael R MacDonald, Vijay Chopra, Seet Yoong Loh, Wataru Shimizu, Imran Zainal Abidin, ASIAN-HF Investigators, A Mark Richards, Javed Butler, Carolyn SP Lam. Electroanatomic Ratios and Mortality in Patients with Heart Failure: Insights from the Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF) Registry. J Am Heart Assoc January 2021 JIF: 4.66
Carolyn SP Lam, Adriaan A. Voors, Piotr Ponikowski, John J.V. McMurray, Scott D. Solomon. Time to rename the Middle Child of Heart Failure: Heart Failure with Mildly Reduced Ejection Fraction. European Heart Journal 2020 Jul 1;41(25):2353-2355. doi: 10.1093/eurheartj/ehaa158. JIF: 22.637
Carolyn SP Lam, Anna Giczewska, Karen Sliwa, Frank Edelmann, Jens Refsgaard, Edimar Bocchi, Justin A. Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Lothar Roessig, Mahesh J. Patel, Burkert Pieske, Kevin J. Anstrom, Paul W. Armstrong, on behalf of the VICTORIA Study Group. Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights from the VICTORIA Trial. JAMA Cardiol. 2021 Jun 1;6(6):706-712. doi: 10.1001/jamacardio.2020.6455. JIF: 12.794
Sanjiv Shah, Sandra Sanders-van Wijk, Jasper Tromp, Lauren Beussink-Nelson, Camilla Hage, Sara Svedlun, Antti Saraste, Stanley Swat, Cynthia Sanchez, Joyce Njoroge, Ru-San tan, Maria Fermer, L-Ming Gan, Lars Lund, Carolyn SP Lam. Proteomic Evaluation of the Comorbidity-Inflammation Paradigm in Heart Failure with Preserved Ejection Fraction: Results from the PROMIS-HFpEF Study. Circulation. October 2020. https://doi.org/10.1161/CIRCULATIONAHA.120.045810 JIF: 23.603
Paul W Armstrong, Carolyn SP Lam, Kevin J Anstrom, Justin Ezekowitz, Adrian F Hernandez, Christopher M O'Connor, Burkert Pieske, Piotr Ponikowski, Sanjiv J Shah, Scott D Solomon, Adriaan A Voors, Lilin She, Vanja Vlajnic, Francine Carvalho, Luke Bamber, Robert O Blaustein, Lothar Roessig, Javed Butler on behalf of the 9 VITALITY-HFpEF Study Group. Effect of Vericiguat versus Placebo on Quality of Life in Patients with Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial. JAMA. 2020. JIF: 45.540
Weiting Huang, Tiew-Hwa Katherine Teng, Wan Ting Tay, A, Mark Richards, Claire A. Lawson, Inder Anand, Carolyn SP Lam. Patient-Reported Outcomes in Heart Failure with Preserved versus Reduced Ejection Fraction: Focus on Physical Independence. ESC Heart Failure. 2020 Aug 30. doi: 10.1002/ehf2.12950. JIF: 3.902
Shun Kohsaka, Carolyn SP Lam, Dae Jung Kim, Matthew A Cavender, Anna Norhammar, Marit E Jørgensen, Kare I Birkeland, Reinhard W Holl, Josep Franch-Nadal, Navdeep Tangri, Jonathan E Shaw, Jenni Ilomäki, Avraham Karasik, Su-Yen Goh, Chern-En Chiang, Marcus Thuresson, Hungta Chen, Eric Wittbrodt, John Bodegård, Filip Surmont, Peter Fenici, Mikhail Kosiborod, CVD-REAL 2 Investigators and Study Group. Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study. Lancet Diabetes Endocrinol. 2020 Jul;8(7):606-615. doi: 10.1016/S2213-8587(20)30130-3. JIF: 25.340
Paul W Armstrong, Burkert Pieske, Kevin J Anstrom, Justin Ezekowitz, Adrian F Hernandez, Javed Butler, Carolyn SP Lam, Piotr Ponikowski, Adriaan A Voors, Gang Jia, Steven E McNulty, Mahesh J Patel, Lotar Roessig, Joerg Koglin, Christopher M O'Connor, VICTORIA Study Group. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction. New England Journal of Medicine. 2020 May 14;382(20):1883-1893. Epub 2020 Mar 28. doi: 10.1056/NEJMoa1915928. JIF: 74.699
Jasper Tromp, Sahiddah Bamadhaj, John G F Cleland, Christiane E Angermann, Ulf Dahlstrom, Wouter Ouwerkerk, Wan Ting Tay, Kenneth Dickstein, George Ertl, Mahmoud Hassanein, Sergio V Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Carolyn SP Lam, Gerasimos Filippatos, Sean P Collins. Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study. Lancet Global Health. 2020 Mar;8(3):e411-e422. doi: 10.1016/S2214-109X(20)30004-8. JIF: 21.597
Jennifer E. Ho; Margaret M. Redfield; Gregory D. Lewis; Walter J. Paulus; Carolyn SP Lam. Deliberating the Diagnostic Dilemma of HFpEF. Circulation. 2020. JIF: 23.603
Sana AI-Khatib, Emelia Benjamin, Christine M Albert, Alvaro Alonso, Cynthia Chauhan, Peng-Sheng Chen, Anne B Curtis, Patrice Desvigne-Nickens, Jennifer E Ho, Carolyn SP Lam, Mark S Link, Kristen K Patton, Margaret M Redfield, Michiel Rienstra, Yves Rosenberg, Renate Schnabel, John A Spertus, Lynne Warner Stevenson, Mellanie True Hills, Adriaan A Voors, Lawton S Cooper, Alan S Go. Advancing Research on the Complex Interrelations between Atrial fibrillation and Heart Failure: A Report from a National Heart, Lung, and Blood Institute Virtual Workshop. URL: https://circ-submit.aha-journals.org. Circulation. 2020 Jun 9;141(23):1915-1926. doi:10.1161/CIRCULATIONAHA.119.045204. JIF: 23.603
Gillian Stein, Tiew-Hwa K Teng, Wan T Tay, A Mark Richards, Robert Doughty, YanHong Dong, David Sim, Poh S D Yeo, Fazlur Jaufeerally, Gerard Leong, Dinna Soon, Lieng H Ling, Carolyn SP Lam. Ethnic Differences in Quality of Life and its Association with Survival in Patients with Heart Failure. Clinical Cardiology. 2020 Sep;43(9);976-985. doi:10.1002/clc.23394. Epub 2020 Jun 20. JIF: 2.248
Stefan D Anker, Javed Butler, Muhammad Shahzeb Khan, William T Abraham, Johann Bauersachs, Edimar Bocchi, Biykem Bozkurt, Eugene Braunwald, Vijay K Chopra, John G Cleland, Justin Ezekowitz, Gerasimos Filippatos, Tim Friede, Adrian F Hernandez, Carolyn SP Lam, JoAnn Lindenfeld, John J V McMurray, Mandeep Mehra, Marco Metra, Milton Packer, Burkert Pieske, Stuart J Pocock, Piotr Ponikowski, Giuseppe M C Rosano, John R Teerlink, Hiroyuki Tsutsui, Dirk J Van Veldhuisen, Subodh Verma, Adriaan A Voors, Janet Wittes, Faiez Zannad, Jian Zhang, Petar Seferovic, Andrew J S Coats. Conducting Clinical Trials in Heart Failure During (and After) the COVID-19 Pandemic: An Expert Consensus Position Paper from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European Heart Journal. 2020 Jun 7;41(22):2109-2117. doi: 10/1093/eurheartj/egaa461. JIF: 22.673
Wouter Ouwerkerk, Tiew-Hwa K Teng, Jasper Tromp, Wan Ting Tay, John G Cleland, Dirk J van Veldhuisen, Kenneth Dickstein, Leong L Ng, Chim C Lang, Stefan D Anker, Faiez Zannad, Chung-Lieh Hung, Jitendra P S Sawhney, Ajay Naik, Wataru Shimizu, Nobuhisa Hagiwara, Gurpreet Singh Wander, Inder Anand, A Mark Richards, Adriaan A Voors, Carolyn SP Lam. Effects of combined renin-angiotensin-aldsterone system inhibitor and beta-blocker treatment on outcomes in heart failure with reduced ejection fraction: insights from BIOSTAT-CHF and ASIAN-HF registries. European Journal of Heart Failure. 2020 Jun 25. doi: 10.1002/ejhf.1869. JIF: 11.627
Wouter Ouwerkerk, Jasper Tromp, Xuanyi Jin, Fazlur Jaufeerally, Poh Shuan Daniel Yeo, Kui Toh Gerard Leong, Hean Yee Ong, Lieng Hsi Ling, Seet Yoong Loh, David Sim, Sheldon Lee, Dinna Soon, Calvin Chin, A. Mark Richards, and Carolyn SP Lam. Heart failure with preserved ejection fraction diagnostic scores in an Asian population. doi:10.1002/ejhf.1851. European Journal of Heart Failure. 2020 May 6. doi: 10.1002/ejhf.1851. JIF: 11.627
Wouter Ouwerkerk, Jasper Tromp, Xuanyi Jin, Fazlur Jaufeerally, Poh Shuan Daniel Yeo, Kui Toh Gerard Leong, Hean Yee Ong, Lieng Hsi Ling, Seet Yoong Loh, David Sim, Sheldon Lee, Dinna Soon, Calvin Chin, A. Mark Richards, Carolyn SP Lam. HFpEF diagnostic scores in an Asian population. European Journal of Heart Failure. 2020. JIF: 11.627
Shun Kohsaka, Carolyn SP Lam, Dae Jung Kim, Matthew A Cavender, Anna Norhammar, Marit E Jørgensen, Kåre I Birkeland, Reinhard W Holl, Josep Franch-Nadal, Navdeep Tangri, Jonathan E Shaw, Jenni Ilomäki, Avraham Karasik, Su-Yen Goh, Chern-En Chiang, Marcus Thuresson, Hungta Chen, Eric Wittbrodt, Johan Bodegård, Filip Surmont, Peter Fenici, Mikhail Kosiborod on behalf of the CVD-REAL Investigators and Study Group. Lower Risk of Cardiovascular Events and Death Associated with Initiation of SGLT-2 Inhibitors in Comparison with DPP-4 Inhibitors – Analysis from CVD-REAL 2, an observational, comparative effectiveness international, collaborative cohort study. The Lancet Diabetes & Endocrinology. 2020. JIF: 25.340
Paul W Armstrong, Burkert Pieske, Kvin J Anstrom, Justin Ezekowitz, Adrian F Hernandez, Javed Butler,Carolyn SP Lam, Piotr Ponikowski, Adriaan A Voors, Gang Jia, Steven E McNulty, Mahesh J Patel, Lothar Roessig, Joerg Koglin, Christopher M O'Connor, VICTORIA Study Group. Vericiguat in Patients with Heart Failure with Reduced Ejection Fraction. New England Journal of Medicine. 2020 May 14;382(20);1883-1893. doi: 10.1056/NEJMoa1915928. Epub 2020 Mar 28. JIF: 74.699
Eugene SJ Tan, Vera Goh, Bernadet T. Santema, Wan Ting Taye, Tiew-Hwa Katherine, Jonathan Yap, Jasper Tromp, Chung-Lieh Hung, Vijay Chopra, Inder Anand, Michael R. MacDonald, Lieng Hsi Ling, Isabelle C. Van Gelder, Michiel Rienstra, Adriaan A. Voors, A. Mark Richards, Carolyn SP Lam. Ethnic differences in atrial fibrillation among patients with heart failure in Asia. ESC Heart Failure. 2020 Aug;7(4);1419-1429. doi: 10.1002/ehf2.12696. Epub 2020 May 8. JIF: 3.902
Carolyn SP Lam, Adriaan A Voors, Ponikowski Piotr, John J V McMurray, Scott D Solomon. Time to rename the Middle Child of Heart Failure: Heart Failure with Mildly Reduced Ejection Fraction. European Heart Journal. 2020 Jul 1;41(25)2353-2355. doi: 10.1093/eurheartj/ehaa158. JIF: 22.673
Justina Motiejūnaitė, Eiichi Akiyama, Alain Cohen-Solal, Aldo Pietro Maggioni, Christian Muellerh, Dong-Ju Choi, Aušra Kavoliūnienė, Jelena Čelutkienė, Jiri Parenica, Johan Lassus, Katsuya Kajimoto, Naoki Sato, Òscar Miró, W. Frank Peacock, Yuya Matsue, Adrian Voors, Carolyn SP Lam, Justin A. Ezekowitz, Ali Ahmed, Greg C. Fonarow^v, Etienne Gayat, Vera Regitz-Zagrosek and Alexandre Mebazaa, on behalf of the GREAT (Global Research on Acute Conditions Team) Network. Gender-related Differences in Long-term outcome in Patients with Acute Heart Failure from different geographic regions. European Heart Journal. 2020. JIF: 22.637
Shijun Xia, Xin Du, Lizhu Guo, Jing Du, Clare Arnott, Carolyn SP Lam, Mark D Huffman, Hisatomi Arima, Yiqiang Yuan, Yang Zheng, Shulin Wu, Xuefeng Guang, Xianhui Zhou, Hongbo Lin, Xiaoshu Cheng, Craig S Anderson, Jianzeng Dong, Changsheng Ma. Sex differences in primary and secondary prevention of cardiovascular disease in China. Circulation. 2020 Feb 18;141(7);530-539. doi: 10.1161/CIRCULATIONAHA.119.043731. Epub 2020 Feb 17. JIF: 23.603
Milton Packer, Carolyn SP Lam, Lars H. Lund, Margaret M. Redfield. Interdependence of Atrial Fibrillation and Heart Failure with a Preserved Ejection Fraction Reflects a Common Underlying Atrial and Ventricular Myopathy. Circulation. 2020 Jan 7:141:4-6. doi:10.1161/CIRCULATIONAHA.119.042996. Epub 2019 Dec 30. JIF: 23.603
Gerasimos Filippatos, Christiane E Angermann, John G F Cleland, Carolyn SP Lam, Ulf Dahlstrom, Kenneth Dickstein, Gero Ertl, Magmoud Hassanein, Kimberly W Hart, Christopher J Lindsell, Sergio V Perrone, Tadhg Guerin, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Sean P Collins. Global Differences in Characteristics, Precipitants and Initial Management of Patients Presenting with Acute Heart Failure. JAMA Cardiology. 2020 Apr 1;5(4);401-410. doi: 10.1001/jamacardio.2019.5108. JIF: 21.597
Xurui Jin, Chanchal Chandramouli, Brooke Allocco, Enying Gong, Carolyn SP Lam, Lijing L Yan. Women's Participation in Cardiovascular Clinical Trials from 2010 to 2017. Circulation. 2020 Feb 18;141(7):540-548. doi: 10.1161/CIRCULATIONAHA.119.043594. Epub 2020 Feb 17. JIF: 23.603
John V McMurray, Alice M Jackson, Carolyn SP Lam, Margaret M Redfield, Inder S Anand, Junbo Ge, Martin P Lefkowitz, Aldo P Maggioni, Felipe Martinez, Milton Packer, Marc A Pfeffer, Burkert Pieske, Adel R Rizkala, Shalini V Sabrarwal, Amil M Shah, Sanjiv V Shah, Victor C Shi, Dirk J Veldhuisen, Faiez Zannad, Michael R Zile, Maja Cikes, Eva Goncalvesova, Tzvetana Katova, Annamaria Kosztin, Malgorzata Lelonek, Nancy Sweitzer, Orly Vardeny, Brian Claggett, Pardeep S Jhund, Scott D Solomon. Effects of sacubitril-valsartan, versus valsartian, in women compared to men with heart failure and preserved ejection fraction: Insights from PARAGON-HF. Circulation. 2020 Feb 4;141(5):338-351. doi: 10:1161/CIRCULATIONAHA.119.044491. Epub 2019 Oct 12. JIF: 23.603
Carolyn SP Lam, Chanchal Chandramouli, Vineeta Ahooja, Subodh Verma. SGLT-2 Inhibitors in Heart Failure: Current Management, Unmet Needs, and Therapeutic Prospects. Journal of the American Heart Association. 2019 Oct 15:8(20):e013389. doi: 10.1161/JAHA.119.013389. Epub 2019 Oct 12. JIF: 4.45
Tiew-Hwa Katherine Teng, Lauren Cooper, Wan Ting Tay, Nancy Luo, Abhinav Sharma, David Whellan, Inder Anand, Ileana L. Pina, Jasper Tromp, A Mark Richards, William Kraus, Christopher M O' Connor, Robert J Mentz, Carolyn SP Lam. Association between body surface area and prescribed doses of guideline-directed medications among international patients with heart failure and reduced ejection fraction. European Journal of Heart Failure. 2020 Apr;22(4);754-758. doi: 10.1002/ejhf.1648. Epub 2019 Dec 18. JIF: 11.627
Scott D Solomon, John J V McMurray, Inder S Anand, Junbo Ge, Carolyn SP Lam, Aldo P Maggioni, Felipe Martinez, Milton Packer, Marc A. Pfeffer, Burkert Pieske, Margaret M Redfield, , Jean L Rouleau, Dirk J van Veldhuisen, Faiez Zannad, Michael R Zile, Akshay S Desai, Brian Claggett, Pardeep S Jhund, Sergey A Boytsov, Josep Comin-Colet, John Cleland, Hans-Dirk Duengen, Eva Goncalvesova, Tzvetana Katova, Jose F Kerr Saraiva, Małgorzata Lelonek, Bela Merkely, Michele Senni, Sanjiv J Shah, Jingmin Zhou, Adel R Rizkala, Jianjian Gong, Victor C Shi, Martin P Lefkowitz. PARAGON-HF Investigators and Committees. Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. The New England Journal of Medicine. 2019 Oct 24;381(17):1609-1620. doi: 10.1056/NEJMoa1908655. Epub 2019 Sep 1. JIF: 74.699
Degang Wu,Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, Nicolas Bertin, Clarabelle Bitong Lin, Chiea Chuen Khor, Michael DeGiorgio, , Shanshan Cheng, Li Bao, Neerja Karnani, Sonia Davila, Patrick Tan, Asim Shabbir, Angela Moh, Eng-King Tan, Jia Nee Foo, Liuh Ling Goh, Khai Pang Leong, Roger S.Y. Foo, Carolyn SP Lam, Arthur Mark Richards, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Huck Hui Ng, Jianjun Liu, and Chaolong Wang. Large-scale whole-genome sequencing of three diverse Asian populations in Singapore. Cell. 2019 Oct 17;179(3):736-749.e15. doi: 10.1016/j.cell.2019.09.019. JIF: 38.637
Jasper Tromp, Camilla Hage, Wouter Ouwerkerk, Sandra Sanders-van Wijk, Sara Svedlund, Antti Saraste, Ulrika Ljung Faxén, Maria Lagerstrom Fermer, Li-ming Gan, Lars H Lund, Sanjiv J Shah, Carolyn SP Lam. Biomarker Correlates of Coronary Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction. Circulation. 2019 Oct 15; 140(16):1359-1361. doi: 10.1161/CIRCULATIONAHA.119.042569. Epub 2019 Oct 14. JIF: 23.603
Jonathan Yap, Wan Ting Tay, Tiew-Hwa Katherine Teng, Inder Anand, A Mark Richards, Lieng Hsi Ling, Michael R MacDonald, Chanchal Chandramouli, Jasper Tromp, Bambang B Siswanto, Michael Zile, John McMurray, Carolyn SP Lam. Association of Diabetes on Cardiac Remodelling, Quality of Life and Clinical Outcomes in Heart Failure with Reduced and Preserved Ejection Fraction. Journal of the American Heart Association. 2019 Sep 3;8(17):e013114. Doi: 10.1161/JAHA.119.013114. Epub 2019 Aug 21. JIF: 4.45
Bernadet T Santema, Wouter Ouwerkerk, Jasper Tromp, Iziah E Sama, Alice Ravera, Vera Regitz-Zagrosek, Hans Hillege, Nilesh J Samani, Faiez Zannad, Kenneth Dickstein, Chim C Lang, John G Cleland, Jozine M Ter Maaten, Marco Metra, Stefan D Anker, Pim van der Harst, Prof. Leong L Ng, Peter van der Meer, Dirk J van Veldhuisen, Sven Meyer, Carolyn SP Lam, ASIAN-HF investigators, Adriaan A Voors. Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational cohort study. Lancet. 2019 Oct 5;394(10205);1254-1263. doi: 10.1016/S0140-6736(19)31792-1. Epub 2019 Aug 22. JIF: 60.392
Mandeep R Mehra, Muthiah Vaduganathan, Min Fu, João Pedro Ferreira, Stefan D Anker, John GF Cleland, Carolyn SP Lam, Dirk J van Veldhuisen, William M Byra, Theodore E Spiro, Hsiaowei Deng, Faiez Zannad, Barry Greenberg. A comprehensive analysis of the effects of rivaroxaban on stroke or transient ischemic attack in patients with heart failure, coronary artery disease, and sinus rhythm: the COMMANDER HF trial. European Heart Journal. 2019 Nov 21;40(44):3593-3602. doi:10.1093/eutheartj/ehz427. JIF: 22.673
Jasper Tromp, Shir Lynn Lim, Wan Ting Tay, Tiew-Hwa Katherine Teng, Chanchal Chandramouli, WouterOuwerkerk, Gupreet SWander, Jitendra PS Sawhney, JonathanYap, Michael R MacDonald, Lieng His Ling, Naveed Sattar, John JV McMurray, A Mark Richards, InderAnand, Carolyn SP Lam, ASIAN-HF investigators. Microvascular disease in patients with Diabetes with heart failure and reduced ejection versus preserved ejection fraction. Diabetes Care. 2019 Sep;42(9):1792-1799. doi: 10/2337/dc18-2515. Epub 2019 July 10. JIF: 15.3
Eugene S J Tan, Wan Ting Tay, Tiew-Hwa Katherine Teng, David Sim, Kui Toh Gerard Leong, Poh Shuan Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Tze Pin Ng, Katrina Poppe, Mayanna Lund, Gerard Devlin, Richard Troughton, Lieng Hsi Ling, Arthur Mark Richards, Robert N Doughty, Carolyn SP Lam. Ethnic Differences in Atrial Fibrillation in Patients with Heart Failure from Asia-Pacific Heart. Heart. 2019 Jun; 105 (11): 842-847. doi: 10.1136/heartjnl-2018-314977. Epub 2019 Jan 19. JIF: 5.420
Yvonne May Fen Chia, Tiew-Hwa K Teng, Wan T Tay, Inder Anand, Michael R MacDonald, Jonathan Yap, Chanchal Chandramouli, A Mark Richards, Jasper Tromp, Wouter Ouwerkerk, Lieng Hsi Ling, Carolyn SP Lam, ASIAN-HF investigators. Prescription patterns of anti-diabetic medications and clinical outcomes in Asian patients with heart failure and diabetes mellitus. European Journal of Heart Failure. 2019 May;21(5):685-688. doi: 10.1002/ejhf.1467. Epub 2019 Apr 29. JIF: 11.627
Jonathan Yap, Shaw Yang Chia, Fang Yi Lim, John C Allen, Louis Teo, David Sim, Yun Yun Go, Fazlur Rehma Jaufeerally, Mattew Seow, Bernard Kwok, Reginald Liew, Carolyn SP Lam. The Singapore Heart Failure Risk Score: Prediction of survival in Southeast Asian patients hospitalised with heart failure. ANNALS of the Academy of Medicine Singapore. 2019 Mar;48(3):86-94. JIF: 1.533
Jasper Tromp, Michael R MacDonald, Wan Ting Tay, Tiew-Hwa K. Teng, Chung-Lieh Hung, Calambur Narasimhan, Wataru Shimizu, Ling Hsi Ling, Tze Pin Ng, Jonathan Yap, John J V McMurray, Michael R Zile, A Mark Richards, Inder S Anand, Carolyn SP Lam. Heart Failure with Preserved Ejection Fraction in the Young. Circulation. 2018 Dec 11;138(24):2763-2773. doi.10.1161/CIRCULATIONAHA.118.034720. JIF: 23.603
Yun Yun Go, Reinhard Sellmair, John C Allen Jr, Anders Sahlén, Heerajnarain Bulluck, David Sim, Fazlur R Jaufeerally, Michael R MacDonald, Zhan Yun Lim, Ping Chai, Seet Yoong Loh, Jonathan Yap, Carolyn SP Lam. Defining a 'frequent admitter' phenotype among patients with repeat heart failure admissions. European Journal of Heart Failure. 2019 Mar;21(3):311-318. doi: 10.1002/ejhf.1348. Epub 2018 Dec 13. JIF: 11.627
Jasper Tromp, Tiew-Hwa Teng, Wan Ting Tay, Chung Lieh Hung, Calambur Narasimhan, Wataru Shimizu, Sang Weon Park, Houng Bang Liew, Tachapong Ngarmukos, Eugene B Reyes, Bambang Siswanto, Checuk-Man Yu, Shu Zhang, Jonathan Yap, Michael MacDonald, Lieng Hsi Ling, Kirsten Leineweber, A Mark Richards, Michael R Zile, Inder S Anand, Carolyn SP Lam, ASIAN-HF Investigators. Heart Failure with Preserved Ejection Fraction in Asia. European Journal of Heart Failure. 2019 Jan;21(1):23-36. doi: 10.1002/ejhf.1227. Epub 2018 Aug 16. JIF: 11.627
Bernadet T Santema, Mariëlle Kloosterman, Isabelle C Van Gelder, Ify Mordi, Chim C Lang, Carolyn SP Lam, Stefan D Anker, John G Cleland, Kenneth Dickstein, Gerasimos Filippatos, Pim van der Harst, Hans L Hillege, Jozine M Ter Maaten, Marco Metra, Leong L Ng, Piotr Ponikowski, Nilesh J Samani, Dirk J Van Veldhuisen, Aeilko H Zwinderman, Faiez Zannad, Kevin Damman, Peter van der Meer, Michiel Rienstra, Adriaan A Voors. Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced versus preserved ejection fraction. European Heart Journal. 2018 Nov 14;39(43):3867-3875. doi: 10.1093/eurheartj/ehy421. JIF: 22.673
Faiez Zannad, Stefan D Anker, William M Byra, John G F Cleland, Min Fu, Mihai Gheorghiade, Carolyn SP Lam, Mandeep R Mehra, James D Neaton, Christopher C Nessel, Theodore E Spiro, Dirk J van Veldhuisen, Barry Greenberg, COMMANDER HF Investigators. Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease. New England Journal of Medicine. 2018 Oct 4;379(14):1332-1342. doi: 10.1056/NEJMoa1808848. Epub 2018 Aug 27. JIF: 74.699
Carolyn SP Lam, Wolfram Doehner, Josep Comin-Colet, IRON CORE Group. Iron deficiency in chronic heart failure: Case-based practical guidance. ESC Heart Failure. 2018 Oct;5(5):764-771. doi: 10.1002/ehf2.12333. Epub 2018 Aug 2. JIF: 3.902
Sanjiv J Shah, Carolyn SP Lam, Sara Svedlund, Antti Saraste, Camilla Hage, Ru-San Tan, Lauren Beussink-Nelson, Maria Lagerstrom Fermer, Malin A Broberg, Li-Ming Gan, Lars H Lund. Prevalence and Correlates of Coronary Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction: PROMIS-HFpEF. European Heart Journal. 2018 Oct 1;39(37):3439-3450. doi: 10.1093/eurheartj/ehy531. JIF: 22.673
Lauren B Cooper, Jonathan Yap, Wan Ting Tay, Tiew-Hwa K Teng, Michael MacDonald, Inder S Anand, Abhinav Sharma, Christopher M O'Connor, William E Kraus, Robert J Mentz, Carolyn SP Lam, HF-ACTION and ASIAN-HF investigators. Multi-Ethnic Comparisons of Diabetes in Heart Failure with Reduced Ejection Fraction: Insights from the HF-ACTION Trial and the ASIAN-HF Registry. European Journal of Heart Failure. 2018 Sep;20(9):1281-1289. doi: 10.1002/ejhf.1223. Epub 2018 Jun 26. JIF: 11.627
Tiew-Hwa K Teng, Jasper Tromp, Wan Ting Tay, Inder Anand, Wouter Ouwerkerk, Vijay Chopra, Gurpreet S Wander, Jonathan Jl Yap, Michael R MacDonald, Chang Fen Xu, Yvonne Mf Chia, Wataru Shimizu, ASIAN-HF investigators, A Mark Richards, Adriaan Voors, Carolyn SP Lam. Prescribing patterns of evidence-based heart failure pharmacotherapy and outcomes in the ASIAN-HF registry: a cohort study. Lancet Global Health. 2018 Sep;6(9):e1008-e1018. doi:10.1016/S2214-109X(18)30306-1. JIF: 21.597
Jiun-Lu Lin, Kuo-Tzu Sung, Cheng-Huang Su, Tzu-Hsun Chou, Chi-In Lo, Jui-Peng Tsai, Shun-Chuan Chang, Yau-Huei Lai, Kuang-Chun Hu, Chia-Yuan Liu, Chun-Ho Yun, Chung-Lieh Hung, Hung-I Yeh, MD, Carolyn SP Lam. Cardiac Structural Remodeling, Longitudinal Systolic Strain and Torsional Mechanics in Lean and Non-lean Dysglycemic Chinese Adults. Circulation: Cardiovascular Imaging. 2018 May;11(5):e007047. doi: 10.1161/CIRCIMAGING.117.007047. JIF 4.780
Vera J Goh, Jasper Tromp, Tiew-Hwa K. Teng, Wan Ting Tay, Peter Van Der Meer, Lieng Hsi Ling, Bambang B Siswanto, Chung-Lieh Hung, Wataru Shimizu, Shu Zhang, Calambur Narasimhan, Cheuk Man Yu, Sang Weon Park, Tachapong Ngarmukos, Houng Bang Liew, Eugenio Reyes, Jonathan Yap, Michael Macdonald, A Mark Richards, Inder Anand, Carolyn SP Lam. Prevalence, clinical correlates and outcomes of anaemia in multiethnic Asian patients with heart failure with reduced ejection fraction. ESC Heart Failure. 2018 Aug;5(4)570-578. doi: 10.1002/ehf2.12279. Epub 2018 Mar 31. JIF: 3.902
Carolyn SP Lam, Greg D Gamble, Lieng H Ling,David Sim, Kui Toh Gerard Leong, Poh Shuan Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Tze P Ng, Vicky A Cameron, Katrina Poppe, Mayanna Lund, Gerry Devlin, Richard Troughton, A Mark Richards*, Robert N Doughty *(*Co-senior authors). Mortality Associated with Heart Failure with Preserved Versus Reduced Ejection Fracton In A Prospective International Multi-Ethnic Cohort Study. European Heart Journal. 2018 May 21;39(20):1770-1780. doi: 10.1093/eurheartj/ehy005. JIF: 22.673
Tee Joo Yeo, Poh Shuan Daniel Yeo, Farid Abdul Hadi, Timothy Cushway, Kim Yee Lee, Fang Fang Yin, Anne Ching, Ruili Li, Seet Yoong Loh, Shir Lynn Lim, Raymond Ching-Chiew Wong, Bee Choo Tai, Arthur Mark Richards, Carolyn SP Lam. Single-dose intravenous iron in Southeast Asian heart failure patients: A pilot randomized placebo-controlled study (PRACTICE-ASIA-HF). ESC Heart Failure. 2018 Apr;5(2):344-353. doi: 10.1002/ehf2.12250. Epub 2018 Jan 18. JIF: 3.902
Yun Yun Go, Tadafumi Sugimoto, Heerajnarain Bulluck, Sanchalika Acharyya, John Carson Allen, Shaw Yang Chia, Fazlur Rehman Jauferally, David Sim, Tiong Keng Lim, Reginald Liew, Carolyn SP Lam. Age and ejection fraction modify the impact of atrial fibrillation on acute heart failure outcomes. European Journal of Heart Failure. 2018 Apr;20(4):821-822. doi: 10.1002/ejhf.1075. Epub 2017 Nov 16. JIF: 11.627
Jasper Tromp, Wan Ting Tay, Wouter Ouwerkerk, Tiew-Hwa Katherine Teng, Jonathan Yap, Michael R MacDonald, Kirsten Leineweber, John J V McMurray, Michael R Zile, Inder S Anand, Carolyn S P Lam, ASIAN-HF authors. Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry. PLOS Medicine. 2018 March 27;15(3):e1002541. doi: 10.1371/journal.pmed.1002541. eCollection 2018 Mar. JIF: 10.500
Thomas M Gorter, Joost P van Melle, Michiel Rienstra, Barry A Borlaug, Yoran M Hummel, Isabelle C van Gelder, Elke S Hoendermis Adriaan A Voors, Dirk J van Veldhuisen, Carolyn SP Lam. Right Heart Dysfunction in Heart Failure with Preserved Ejection Fraction: The Impact of Atrial Fibrillation. Journal of Cardiac Failure. 2018 Mar;24(3):177-185. doi: 10.1016/j-cardfail.2017.11.005. Epub 2017 Nov 29. JIF: 3.942.
Jasper Tromp, A Mark Richards, Wan Ting Tay, Tiew-Hwa K Teng, Poh Suan, Daniel Yeo, David Sim, Fazlur Jaufeerally, Gerard Leong, Hean Yee Ong, Lieng Hsi Ling, Dirk J van Veldhuisen, Tiny Jaarsma, Adriaan A Voors, Peter van der Meer, Rudolf de Boer*, Carolyn SP Lam* (*corresponding author). NT-proBNP and Prognosis in Caucasian versus Asian Patients with Heart Failure. Short title: Ethnicity and NT-proBNP in Heart Failure. ESC Heart Failure. 2017. JIF: 3.902
Chung-Lieh Hung, Szu-Hua Pan, Chia-Li Han, Ching-Wei Chang, Yuan-Ling Hsu, Cheng-Huang Su, Shou-Chuan Shih, Yu-Jun Lai, Jen-Shiu Chiang Chiau, Hung-I Yeh, Chia-Yuan Liu, Hung-chang Lee, Carolyn SP Lam. Membrane Proteomics of Impaired Energetics and Cytoskeletal Disorganization in Elderly Diet-Induced Diabetic Mice. Journal of Proteome Research. 2017 Oct 6;16(10):3504-3513. doi: 10.1021/acs.jprotemome.7b00148. Epub 2017 Sep 13. JIF: 4.268
Carolyn SP Lam, Karen Barry, Amit Khera. Medical Podcasting and Circulation On the Run: Why, How and What Now. Circulation. 2017 Aug 8;136(6):513-515. doi: 10.1161/CIRCULATIONAHA.117.029760. JIF: 23.603
Yau-Huei Lai, Ming-En Liu, Cheng-Huang Su, Chun-Ho Yun, Chia-Yuan Liu, Charles Jia-Yin Hou, Kuang-Chun Hu, Chung-Lieh Hung, Hung-I Yeh, Carolyn SP Lam. Obesity-Related Changes In Cardiac Structure And Function Among Asian Men And Women. Journal of the American College of Cardiology. 2017 Jun 13;69(23)2876-2878. doi: 10.1016/j.jacc.2017.04.016. JIF: 18.639
Chih-Hsuan Yen, Kuang-Te Wang, Ping-Ying Lee, Chuan-Chuan Liu, Ya-Ching Hsieh, Jen-Yuan Kuo, Bernard E. Bulwer, Chung-Lieh Hung, Shun-Chuan Chang, Shou-Chuan Shih, Kuang-Chun Hu, Hung-I Yeh, Carolyn SP Lam. Gender-Differences in the Associations between Circulating Creatine Kinase, Blood Pressure, Body Mass and Non-Alcoholic Fatty Liver Disease in Asymptomatic Asians. PLOS ONE. 2017 Jun 30;12(6):e0179898. doi: 10.1371/journal.pone.0179898. eCollection 2017. JIF: 2.740
Carolyn SP Lam, Scott D Solomon. Fussing Over The Middle Child: Heart Failure With Mid-Range Ejection Fraction. Circulation. 2017 Apr 4;135(14):1279-1280. doi: 10.1161/CIRCULATIONAHA.117.027324. JIF: 23.603
Burkert Pieske, Aldo Maggioni, Carolyn SP Lam, Elisabeth Pieske-Kraigher, Gerasimos Filippatos, Javed Butler, Piotr Ponikowski, Sanjiv J. Shah, Scott D. Solomon, Andrea-Viviana Scalise, Katharina Mueller, Lothar Roessig, Mihai Gheorghiade. Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) study. European Heart Journal. 2017 Apr 14;38(15):1119-1127. doi: 10.1093/eurheartj/ehw593. JIF: 22.673
Carolyn SP Lam, Michiel Rienstra, Wan Ting Tay, Licette C Y Liu, Yoran M Hummel, Peter van der Meer, Rudolf A de Boer, Isabelle C Van Gelder, Dirk J van Veldhuisen, , Adriaan A Voors, Elke S Hoendermis. Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction: Association with Exercise Capacity, Left Ventricular Filling Pressures, Natriuretic Peptides, and Left Atrial Volume. JACC Heart Failure. 2017 Feb;5(2);92-98. doi: 10.1016/j.jchf.2016.10.005. Epub 2016 Dec 21. JIF: 8.750
Carolyn SP Lam, Tiew-Hwa Katherine Teng, Wan Ting Tay, Inder Anand, Shu Zhang, Wataru Shimizu, Calambur Narasimhan, Sang Weon Park, Cheuk-Man Yu, Tachapong Ngarmukos, Razali Omar, Eugene B Reyes, Bambang B Siswanto, Chung-Lieh Hung, Lieng H Ling, Jonathan Yap, Michael MacDonald, A Mark Richards. Regional and ethnic differences among patients with heart failure in Asia: the asian sudden cardiac death in heart failure registry. European Heart Journal. 2016 Nov 1; 37(41):3141-3153. doi: 10.1093/eurheartj/ehw331. Epub 2016 Aug 7. JIF: 22.673
Lijing L Yan, Heng Jiang, Carolyn SP Lam. Random Plasma Glucose Levels and Cardiovascular Risk. JAMA Cardiology. 2016 Oct 1;1(7):823-824. doi: 10.1001/jamacardio.2016.1802. JIF: 12.794
Crystel M Gijsberts, Lina Benson, Ulf Dahlström, David Sim, Daniel P S Yeo, Hean Yee Ong, Fazlur Jaufeerally, Gerard K T Leong, Lieng H Ling, A Mark Richards, Dominique P V de Klejin, Lars H Lund, Carolyn SP Lam. Ethnic differences in the association of QRS duration with ejection fraction and outcome in heart failure. Heart. 2016 Sep 15;102(18);1462-71. doi: 10.1136/heartjnl-2015-309212. Epub 2016 Jul 11. JIF: 5.420
Jonathan Yap, Ai Zhen Jin, Shwe Zin Nyunt, Tze Pin Ng, A Mark Richards, Carolyn SP Lam. Longitudinal Community-Based Study of QT Interval and Mortality in Southeast Asians. PLoS One. 2016 May 5;11(5) e0154901. doi: 10.1371/journal.pone.0154901. eCollection 2016. JIF: 2.740
Carolyn SP Lam, Lars H Lund. Microvascular endothelial dysfunction in heart failure with preserved ejection fraction. Heart. 2016 Feb 15; 102(4):257-9. doi: 10.1136/heartjnl-2015-308852. JIF: 5.420
Michelle M Y Chan, Rajalakshmi Santhanakrishnan, Jenny PC Chong, Zhaojin Chen, Bee Choo Tai, Oi Wah Liew, Tze Pin Ng, Lieng H Ling, David Sim, Kui Toh G Leong, Poh Shuan Daniel Yeo, Hean-Yee Ong, Fazlur Jaufeerally, Raymond Ching-Chiew Wong, Chai Ping, Adrian F Low, Arthur Mark Richards, Carolyn SP Lam. Growth Differentiation Factor 15 in Heart Failure with Preserved versus Reduced Ejection Fraction. European Journal of Heart Failure. 2016 Jan; 18(1):81-8. JIF: 11.627

Research Trials

2022 Baseline and repeat NT-proBNP in patients with Heart Failure
2021 Arresting Heart Disease in Diabetics, SingHealth Duke NUS Cardiovascular Sciences Academic Clinical Programme
2020-2024 Asian Diabetes Outcomes Prevention Trial (ADOPT), NMRC CTG-ICT
2019-2023 Cardiovascular Clinical Trials in Asia: Asian Diabetes Outcomes Prevention Trial (ADOPT), NMRC Clinician Scientist Award
2019-2023 Cardiovascular Clinical Trials in Asia: Asian Diabetes Outcomes Prevention Trial (ADOPT), Roche Diagnostics
2019-2023 Early Phase Experimental Cardiovascular Trial Unit, Bayer
2017-2018 eKo.ai, A*Star
2017-2018 Asian Sudden Cardiac Death in Heart Failure 2 (ASIAN-HF2 study), Bayer
2015-2018 Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF study), Bayer
2015-2017 Asian Diabetes Outcomes Registry (ADORE)
2015 Metabolomic Profiling In Heart Failure With Preserved Vs Reduced Ejection Fraction
2015-2017 Coronary Flow Reserve in Heart Failure with Preserved Ejection Fraction (CFR-HFpEF)
2015-pre Programme Lead of the Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT), A*Star BMRC
2014-2019 NMRC Clinician Scientist Award: Clinical Trials in Heart Failure
2014-2017 Toll-like receptor 2 as a therapeutic target in heart failure
2014-2016 Randomised, controlled pilot study to assess the role of IV ferric carboxymaltose in Asian patients with HF
2014-2019 REnal SymPathECTomy in Heart Failure (RESPECT-HF) Study
2014 Electrocardiographic Parameters in Asian Versus Western Adults
2013-2018 Theme 1 of National Medical Research Council Centre Grant
2013 A randomized, double-blind, crossover study to assess the effects of LCZ696 and valsartan in Asian patients with salt-sensitive hypertension
2011-2016 Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF study), Boston Scientific
2010-2012 Outcome in Patients with Heart Failure with a Preserved Left Ventricular Ejection Fraction (the “PEOPLE” study)
2010-2013 Prospective compArison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fraction “PARAMOUNT”, Novartis
2009-2012 Biomarkers and Management of Cardiovascular Disease: Singapore, Heart Failure Outcomes and Phenotypes (the “SHOP” study)