Chronic Myeloid Leukemia

​Chronic myeloid leukemia (CML) is a type of blood cancer. In CML, there is increase generation of immature white blood cells as a result of the acquisition of an abnormal chromosome called the Phildelphia chromosome.  This results in the abnormal gene mutation called BCR-ABL. CML is a slow glowing leukaemia and most patients are diagnosed at this chronic phase. Rarely, some patients may have a faster progressive form  and are diagnosed at later stages called accelerated or blast phase where the leukemia transforms into  acute leukemia.